Trifluoroacetic acid → HCID 117622904, compound

Participants

Reaction Steps

195 mg (0.29 mmol) of tert-butyl 4-{[2-{4-[5-chloro-2-(difluoromethoxy)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}-4-(trifluoromethoxy)butanoyl]amino}benzoate (racemate) were hydrolysed with TFA according to General Method 2. The crude product was purified by preparative HPLC (Reprosil C18, water/acetonitrile gradient). Yield: 84 mg (50% of theory)

Provenance & Evidence