HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-amino-4-fluoro-1H-indazol-3-ol → HCID 117622637, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-amino-4-fluoro-1H-indazol-3-ol | HCID 24728152 | — |
| Reactant | 2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]butanoic acid | HCID 117622569 | — |
| Product | HCID 117622637 | HCID 117622637 | — |
Reaction Steps
100 mg (0.28 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]butanoic acid (racemate) and 51 mg (0.31 mmol, 1.1 eq.) of 6-amino-4-fluoro-1,2-dihydro-3H-indazol-3-one were reacted according to General Method 6. The crude product was purified by preparative HPLC (Reprosil C18, water/acetonitrile gradient). Yield: 6 mg (4% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-db40c00db3aa41238a37d39e07591fbc |
| Source note | uspto-grants-2016_09 |