Phenacylamine → HCID 178481978, compound

Participants

Reaction Steps

Using the general procedure, the title compound was synthesized from methyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide and aminoacetophenone, using a reaction time for the amidine formation of 3.5 hours. Yield 34%. δH (DMSO-d6): 9.69 (2H, m), 9.51 (1H, bs), 9.22 (1H, s), 8.07-8.05 (2H, m), 7.78-7.73 (1H, m), 7.65-7.61 (2H, m), 5.24 (2H, d, J=6.0), 4.06 (3H, s).

Provenance & Evidence