Ethanone, 2-amino-1-phenyl-, hydrochloride (1:1) → HCID 178456701, compound

Participants

Reaction Steps

Using the general procedure, the title compound was synthesized from methyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide and aminoacetophenone hydrochloride, using a reaction time of 5 hours and 30 minutes for the amidine formation. Yield 29%. δH (DMSO-d6): 9.74 (2H, m), 9.54 (1H, bs), 9.25 (1H, s), 8.07-8.05 (2H, m), 7.78-7.73 (1H, m), 7.65-7.61 (2H, m), 5.27-5.24 (4H, m), 3.62 (1H, t, J=2.5).

Provenance & Evidence