HCID 86681667, compound → HCID 86681666, compound

Participants

Reaction Steps

A solution of benzyl 2-(5-(methylsulfonamido)indolin-1-yl)acetate (0.565 g, 1.568 mmol) in methanol was added to a suspension of 10% w/w Pd/C (a catalytic amount) in water and the mixture was hydrogenated in a Parr apparatus at 30 psi overnight. The catalyst was filtered off and the filtrate was evaporated to dryness affording 2-(5-(methylsulfonamido)indolin-1-yl)acetic acid (0.351 g, 1.299 mmol, 83% yield). MS/ESI+ 271.0 [MH]+.

Provenance & Evidence