Toluene → HCID 59774430, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of t-butyl carbazate (25.5 g, 193 mmol) in THF (60 ml) was added 47% ethyl glyoxylate in toluene (polymer type) (46.1 g, 212 mmol), and stirred at 60° C. for minutes. The reaction solution was cooled to room temperature, and concentrated under reduced pressure. The resulting solid was washed with a mixed solvent of hexane:ethyl acetate=5:1 to give 33.9 g of Compound (X-1) (yield: 80%) as colorless solid.

Provenance & Evidence