HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 3-chloro-6,7,8,9-tetrahydro-5H-1,2,7-triaza-benzocycloheptene trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-Chloro-5,6,8,9-tetrahydro-1,2,7-triaza-benzocycloheptene-7-carboxylic acid tert-butyl ester | HCID 86686055 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-chloro-6,7,8,9-tetrahydro-5H-1,2,7-triaza-benzocycloheptene trifluoroacetate | HCID 86697867 | — |
Reaction Steps
0.15 g (0.53 mmol) 3-chloro-5,6,8,9-tetrahydro-1,2,7-triaza-benzocycloheptene-7-carboxylic acid tert-butyl ester (CAS: 1251001-53-2), 0.4 mL trifluoroacetic acid and 2 mL DCM were stirred at RT for 4 hours. The reaction was concentrated to dryness. Yield: 0.16 g (quantitativ). ESI-MS: m/z=184/186 (M+H)+; Rt(HPLC): 0.41 min (Method K).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029360B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-152cf5efd1cc4388b73d9efea802af8b |
| Source note | uspto-grants-2015_05 |