Dimethylformamide → HCID 71748042, compound

Participants

Reaction Steps

To 0.03 g (0.12 mmol) 6-bromo-pyrazolo[1,5-A]pyrimidine-2-carboxylic acid, 0.12 mmol 2-chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine hydrochloride and 0.51 mmol triethyl amine (TEA) in 1.5 ml dimethylformamide (DMF) 0.14 mmol TBTU (O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate) was added and the reaction mixture was stirred at RT for 1 h. Water was added to the reaction mixture. The precipitate was collected and dried. Yield: 0.018 g (36% of theory). ESI-MS: m/z=406 (M+H)+; Rt(HPLC): 1.29 min. (Method J).

Provenance & Evidence