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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57197Generated: October 25, 2026

Dioxindole → HCID 67087479, compound

https://huagongshe.com/reaction/57197

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDioxindoleHCID 6097—
ReactantBenzenesulfonyl chlorideHCID 7369—
ReactantSulfuryl chlorideHCID 24648—
ReactantHCID 67087479HCID 67087479—
ProductHCID 67087479HCID 67087479—
Product3-Amino-1-phenylsulfonyl-5-chloro-3-(2-ethoxypyridin-3-yl)-6-fluoro-1,3-dihydro-indol-2-oneHCID 67087684—

Reaction Steps

The title compound was prepared in analogy to example 1.1 to 1.3 using 5-chloro-3-(2-ethoxypyridin-3-yl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-one as 3-hydroxy-1,3-dihydroindol-2-one IV and phenylsulfonyl chloride as sulfonyl chloride VII. 5-Chloro-3-(2-ethoxypyridin-3-yl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-one was prepared in analogy to example a.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434713B2
Source datasetuspto-grants-2016_09
ORD IDord-efb3dbfc6748417fae27f4a12823d827
Source noteuspto-grants-2016_09