HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86704975, compound → HCID 86704978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86704975 | HCID 86704975 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86704978 | HCID 86704978 | 62.4% |
Reaction Steps
A suspension of 1-[4-(benzyloxy)phenyl]-3-methoxy-1H-pyrazolo[3,4-b]pyridine (1.1 g) and 10% palladium on carbon (containing water (50%), 0.10 g) in methanol (50 ml) was stirred for 3 hr under a hydrogen atmosphere at room temperature. The reaction mixture was filtered through celite, and the filtrate was purified by silica gel column chromatography (hexane/ethyl acetate) to give the title compound (0.50 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029388B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-89a34f337491435ebb79d362bcd2016e |
| Source note | uspto-grants-2015_05 |