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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 572174Generated: November 1, 2026

1-[4-(Benzyloxy)phenyl]-3-ethyl-1H-pyrazolo[3,4-b]pyridine → 4-(3-Ethyl-1H-pyrazolo[3,4-b]pyridin-1-yl)phenol

https://huagongshe.com/reaction/572174

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(Benzyloxy)phenyl]-3-ethyl-1H-pyrazolo[3,4-b]pyridineHCID 86704982—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product4-(3-Ethyl-1H-pyrazolo[3,4-b]pyridin-1-yl)phenolHCID 8670498391.8%

Reaction Steps

A mixture of 1-[4-(benzyloxy)phenyl]-3-ethyl-1H-pyrazolo[3,4-b]pyridine (300 mg), 10% palladium on carbon (containing water (50%), 97 mg) and ethanol (10 ml) was vigorously stirred under a hydrogen atmosphere at room temperature for 5 hr. The reaction mixture was filtered and the filtrate was concentrated to give the title compound (200 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029388B2
Source datasetuspto-grants-2015_05
ORD IDord-f2f8545161374690b7943275a958663c
Source noteuspto-grants-2015_05