p-(Trifluoromethoxy)phenyl isocyanate → HCID 86713751, compound

Participants

Reaction Steps

Compound 2576 was prepared in 70% yield from 4-(trifluoromethoxy)phenyl isocyanate using the procedure detailed for compound 2221 in Example 4. 1H NMR (300 MHz, DMSO-d6): δ 8.75 (q, J=5 Hz, 1H), 8.45 (d, J=6 Hz, 1H), 7.33 (d, J=3 Hz, 1H), 7.07 (dd, J=6 and 3 Hz, 1H), 6.86 (d, J=9 Hz, 2H), 6.64 (d, J=9 Hz, 2H), 5.19 (br s, 2H), 2.77 (d, J=5 Hz, 3H).

Provenance & Evidence