HRID572315

反应详情

EQUATION

反应方程式

HRID 572315 的结构方程式

PROCEDURE

实验过程

Prepared from 5-(5-Trifluoromethyl-4-methyl-isoxazol-3-yl)-thiophene-2-carbonyl chloride (74 mg, 0.25 mmol, as prepared in Example 2 Method B) and (S)-1-piperidin-3-yl-methanol, hydrochloride (76 mg, 0.5 mmol) by the method used in Example 46 for the achiral isomer. Gummy solid (70 mg, 74%). LC/MS 5.85 min, [M+1]+ 375.

WORKUP

后处理

  1. customLC/MS 5.85 min, [M+1]+ 375