HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid benzylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | HCID 178434647 | HCID 178434647 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid benzylamide | HCID 178434650 | 13.4% |
Reaction Steps
the title compound (16 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride (100 mg, 0.30 mmol), benzylamine (66 μL, 0.60 mmol) and PS-NMM (0.320 g, 0.60 mmol) in 5 mL of methanol. MS (m/z, ES+): 400.5 (M+1, 100%). Yield=13%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434720B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-6e5fb02fb01b44ed87a7ebeb846c1036 |
| Source note | uspto-grants-2016_09 |