Methyl 2-bromopropionate → HCID 66652969, compound

HRID 572560Notes

Reaction equation

HRID 572560 reaction equation
[CH3:1][NH:2][CH:3]([C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[C:8]#[N:9])[CH3:4].Br[CH:14]([CH3:19])[C:15]([O:17][CH3:18])=[O:16]>>[C:8]([C:7]1[CH:6]=[C:5]([CH:3]([N:2]([CH3:1])[C@H:14]([C:15]([O:17][CH3:18])=[O:16])[CH3:19])[CH3:4])[CH:12]=[CH:11][CH:10]=1)#[N:9]

Participants

3

Reactant 2

HCID 95576Methyl 2-bromopropionateHCID 43754893HCID 43754893, compound

Product 1

HCID 66652969HCID 66652969, compound

Procedure

Compound was prepared following the general procedure 11 starting from 3-[1-(methylamino)ethyl]benzonitrile and methyl 2-bromopropionate, affording the title compound as a colorless oil. HPLC (Method A) Rt 1.54 min (Purity: 74%).

Workup

  1. customCompound was prepared

Sources & evidence

ORD record
ord-d9e176b390104ba89d5a1b10a456430c
Source dataset
uspto-grants-2015_05
Patent number
US09029405B2

Reaction notes

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