Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methylmorpholine → 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-aminobenzylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methylmorpholine | HCID 7972 | — |
| 반응물 | 4-Aminobenzylamine | HCID 427814 | — |
| 반응물 | HCID 178434647 | HCID 178434647 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)benzothiazole-6-sulfonic acid 4-aminobenzylamide | HCID 178434653 | 12.1% |
반응 단계
the title compound (15 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride (100 mg, 0.30 mmol), 4-aminomethylphenylamine (69 μL, 0.60 mmol) and PS-NMM (0.320 g, 0.60 mmol) in 5 mL of methanol. MS (m/z, ES+): 415.4 (M+1, 100%). Yield=12%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434720B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-4b0ecdb954e74e58a791dfea2be305b4 |
| 출처 메모 | uspto-grants-2016_09 |