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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 572755Generated: October 31, 2026

3-Fluoro-5-methylaniline → HCID 52913592, compound

https://huagongshe.com/reaction/572755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-5-methylanilineHCID 2778458—
Reactant8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromideHCID 67103675—
ProductHCID 52913592HCID 5291359258.4%

Reaction Steps

3-fluoro-5-methylaniline (0.091 mL, 0.82 mmol) was reacted with 8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromide (0.1 g, 0.20 mmol) using an analogous procedure to the one described in Example 3.03 to give 8-(1-(3-fluoro-5-methylphenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (0.053 g, 57%) as a white solid. Mass Spectrum: M+H+ 454.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029374B2
Source datasetuspto-grants-2015_05
ORD IDord-83cd49853ba04139a65bec72f13c038b
Source noteuspto-grants-2015_05