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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 572760Generated: November 1, 2026

3-Amino-4-methylbenzonitrile → HCID 58235081, compound

https://huagongshe.com/reaction/572760

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-methylbenzonitrileHCID 7016428—
Reactant8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromideHCID 67103675—
ProductHCID 58235081HCID 5823508154.3%

Reaction Steps

3-amino-4-methylbenzonitrile (108 mg, 0.82 mmol) was reacted with 8-(1-bromoethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide hydrobromide (100 mg, 0.20 mmol) using an analogous procedure to the one described in Example 3.03 to give 8-(1-(5-cyano-2-methylphenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (50 mg, 53%) as a white solid. Mass Spectrum: M+H+ 461.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029374B2
Source datasetuspto-grants-2015_05
ORD IDord-9972028132a9494199c43848f41548fb
Source noteuspto-grants-2015_05