HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl (6-chloropyridin-3-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(6-Chloropyridin-3-yl)acetic acid | HCID 14071571 | — |
| Product | Methyl (6-chloropyridin-3-yl)acetate | HCID 53419528 | — |
Reaction Steps
To a solution of 2-(6-chloropyridin-3-yl)acetic acid (2 g, 117 mmol) in methanol (40 ml) was added SOCl2 (1.38 g, 117 mmol). The reaction mixture was concentrated after two hours to give the desired product. LC-MS: m/z (M+H)=186.6
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029531B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-6c96a62044b2478baa67244db517eacb |
| Source note | uspto-grants-2015_05 |