Morpholine → HCID 178434642, compound

HRID 57301Notes

Reaction equation

HRID 57301 reaction equation
Br[CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[N:7]=[C:8]([C:10]3[C:14]([CH3:15])=[N:13][NH:12][C:11]=3[NH2:16])[S:9][C:5]=2[CH:4]=1.[NH:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[CH3:15][C:14]1[C:10]([C:8]2[S:9][C:5]3[CH:4]=[C:3]([CH2:2][N:19]4[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)[CH:18]=[CH:17][C:6]=3[N:7]=2)=[C:11]([NH2:16])[NH:12][N:13]=1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 178434639HCID 178434639, compound

Product 1

HCID 178434642HCID 178434642, compound

Procedure

The title compound (27 mg) was prepared starting from 40 mg of 4-(6-bromomethylbenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine and excess morpholine. MS (m/z, ES+): 330.1 (M+1, 30%), 243 (M−O(CH2)4N, 100%).

Sources & evidence

ORD record
ord-dcbfaddd64304d8384d71d9745aaa9fe
Source dataset
uspto-grants-2016_09
Patent number
US09434720B2

Reaction notes

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