Monobenzone → 4-(2-(4-(Benzyloxy)phenoxy)ethyl)morpholine

HRID 573068Notes

Reaction equation

HRID 573068 reaction equation
Cl[CH2:2][CH2:3][N:4]([CH3:6])[CH3:5].[CH2:7]([O:14][C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH2:22]([O:29][C:30]1C=C(O)C=CC=1)C1C=CC=CC=1>>[CH2:7]([O:14][C:15]1[CH:16]=[CH:17][C:18]([O:21][CH2:2][CH2:3][N:4]2[CH2:6][CH2:30][O:29][CH2:22][CH2:5]2)=[CH:19][CH:20]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

Participants

4

Reactant 3

HCID 7638MonobenzoneHCID 79012-Chloro-N,N-dimethylethylamineHCID 138048Benzyl 3-hydroxyphenyl ether

Product 1

HCID 22969504-(2-(4-(Benzyloxy)phenoxy)ethyl)morpholine

Procedure

The title compound was prepared by substituting 4-(2-chloroethyl)morpholine for 2-chloro-N,N-dimethylethanamine and 4-(benzyloxy)phenol for 3-(benzyloxy)phenol in EXAMPLE 39A.

Sources & evidence

ORD record
ord-14da5a5aa8d647c094993c0577e518cb
Source dataset
uspto-grants-2015_05
Patent number
US09029404B2

Reaction notes

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