HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methyl-1H-indol-5-ol → 2-(2-Amino-pyridin-4-yloxy)-4-fluoro-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methyl-1H-indol-5-ol | HCID 83336 | — |
| Reactant | Benzoic acid, 2,4-difluoro-, ethyl ester | HCID 2737170 | — |
| Reactant | HCID 178507942 | HCID 178507942 | — |
| Product | 2-(2-Amino-pyridin-4-yloxy)-4-fluoro-benzoic acid methyl ester | HCID 67227884 | — |
Reaction Steps
The title compound was prepared by substituting methyl 2,4-difluorobenzoate for ethyl 2,4-difluorobenzoate and 2-aminopyridin-4-ol for 2-methyl-5-indolol in EXAMPLE 3A, except here heating was at 130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029404B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-3b599d003da043559b397b090ff61417 |
| Source note | uspto-grants-2015_05 |