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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57314Generated: October 29, 2026

6-(Difluoromethoxy)-1H-indole → 6-(difluoromethoxy)-1H-indole-3-carboxylic acid

https://huagongshe.com/reaction/57314

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Difluoromethoxy)-1H-indoleHCID 53844630—
Reactant5-(difluoromethoxy)-1H-indole-3-carboxylic acidHCID 57646514—
Product6-(difluoromethoxy)-1H-indole-3-carboxylic acidHCID 57646513—

Reaction Steps

Prepared as for 5-(difluoromethoxy)-1H-indole-3-carboxylic acid (Example 6) starting with 6-difluoromethoxyindole (WO 97/45408 A1). MS (m/e) 227.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434724B2
Source datasetuspto-grants-2016_09
ORD IDord-56d006d4d2214a268094888eb31046d4
Source noteuspto-grants-2016_09