2-methyl-1H-indol-5-ol → HCID 67227617, compound

HRID 573219Notes

Reaction equation

HRID 573219 reaction equation
CC1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7](O)=[CH:6][CH:5]=2.F[C:13]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:14]=1[C:15]([O:17][CH3:18])=[O:16].FC1C=C(F)C=CC=1C(OCC)=[O:28]>>[NH2:3][C:4]1[C:9]([CH3:10])=[C:8]([CH:7]=[CH:6][CH:5]=1)[O:28][C:13]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:14]=1[C:15]([O:17][CH3:18])=[O:16]

Participants

4

Reactant 3

HCID 833362-methyl-1H-indol-5-olHCID 2737170Benzoic acid, 2,4-difluoro-, ethyl esterHCID 2782897Methyl 2,4-Difluorobenzoate

Product 1

HCID 67227617HCID 67227617, compound

Procedure

The title compound was prepared by substituting 3-amino-2-methylphenol for 2-methyl-5-indolol and methyl 2,4-difluorobenzoate for ethyl 2,4-difluorobenzoate in EXAMPLE 3A.

Sources & evidence

ORD record
ord-6122380c9d9e495b8df9131ee38cbe5a
Source dataset
uspto-grants-2015_05
Patent number
US09029404B2

Reaction notes

Loading…