HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetic acid → HCID 58242748, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetic acid | HCID 596118 | — |
| Reactant | HCID 66911451 | HCID 66911451 | — |
| Product | HCID 58242748 | HCID 58242748 | — |
Reaction Steps
3-[4-(Ethoxycarbonyl)-1,3-thiazol-2-yl]piperidinium chloride (VI-2, 5.32 g) is reacted analogously to Example IV-1 with [5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (4.00 g). This gives, after chromatographic purification, ethyl 2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-3-yl)-1,3-thiazole-4-carboxylate (5.7 g, 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029549B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-c28a185abcae4a5e92ef85ef11146e59 |
| Source note | uspto-grants-2015_05 |