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HRID573258

反应详情

EQUATION

反应方程式

HRID 573258 的结构方程式

REACTANTS

反应物

2
结构：Oc1cccc2ccccc12
HCID7005

1-Naphthol

C10H8O

结构：CC(C)(C)OC(=O)N1CCC(c2nc(C(=O)O)cs2)CC1
HCID2795531

2-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1,3-thiazole-4-carboxylic acid

C14H20N2O4S

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(c2nc(C(=O)Oc3cccc4ccccc34)cs2)CC1
HCID44469316

未命名化合物

PROCEDURE

实验过程

A solution of 2-[1-(tert-butoxycarbonyl)piperidin-4-yl]-1,3-thiazole-4-carboxylic acid (VIII-1, 12.0 g) is reacted analogously to Example IX-1 with 1-naphthol (7.20 g). This gives, after chromatographic purification, tert-butyl 4-{4-[(1-naphthyloxy)carbonyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate (12.3 g, 73%)

WORKUP

后处理

  1. customThis gives, after chromatographic purification, tert-butyl 4-{4-[(1-naphthyloxy)carbonyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate (12.3 g, 73%)