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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 573266Generated: October 29, 2026

HCID 66728062, compound → HCID 86688956, compound

https://huagongshe.com/reaction/573266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66728062HCID 66728062—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
ProductHCID 86688956HCID 8668895698.7%

Reaction Steps

A mixture of 1-methyl-3-(4-nitrophenyl)-1H-pyrrolo[3,2-b]pyridine (85 mg) and 10% Pd—C (50% wet, 100 mg) in MeOH (4 mL) and AcOEt (4 ml) was stirred under H2 atmosphere (balloon) for 4 h. After this time, the reaction was filtered and the filtrate was concentrated under reduced pressure to give the title compound (74 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029536B2
Source datasetuspto-grants-2015_05
ORD IDord-1ed33ae3e03047f29639ca9012130cf9
Source noteuspto-grants-2015_05