HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66728062, compound → HCID 86688956, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66728062 | HCID 66728062 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86688956 | HCID 86688956 | 98.7% |
Reaction Steps
A mixture of 1-methyl-3-(4-nitrophenyl)-1H-pyrrolo[3,2-b]pyridine (85 mg) and 10% Pd—C (50% wet, 100 mg) in MeOH (4 mL) and AcOEt (4 ml) was stirred under H2 atmosphere (balloon) for 4 h. After this time, the reaction was filtered and the filtrate was concentrated under reduced pressure to give the title compound (74 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029536B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-1ed33ae3e03047f29639ca9012130cf9 |
| Source note | uspto-grants-2015_05 |