Water → HCID 86688963, compound

Participants

Reaction Steps

A mixture of 1-(1H-benzimidazol-2-yl)-5-(1-ethyl-1H-pyrazolo[4,3-b]pyridin-3-yl)pyridin-2(1H)-one (20 mg), MeI (11.95 mg) and Cs2CO3 (36.6 mg) in DMF (1 mL) was stirred at room temperature for 12 h, treated with water, and extracted with AcOEt. The organic layer was dried over MgSO4 and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (AcOEt/hexane) and crystallized from hexane/AcOEt to give the title compound (12 mg).

Provenance & Evidence