HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 573344Generated: October 30, 2026
Diisopropylethylamine → HCID 178463033, compound
https://huagongshe.com/reaction/573344
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Formamidine acetate | HCID 160693 | — |
| Reactant | Methyl 4-amino-1-ethyl-1H-pyrazole-5-carboxylate | HCID 54775640 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 178463033 | HCID 178463033 | 86.6% |
Reaction Steps
A mixture of methyl 4-amino-1-ethyl-1H-pyrazole-5-carboxylate (1.75 g), formamidine acetate (1.615 g), n-butanol (20 mL) and DIPEA (20 mL) was stirred at 120° C. for 3 h. The mixture was concentrated under reduced pressure, and the residual crystals were washed with AcOEt/hexane to give the title compound (1.47 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09029536B2 |
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| Source dataset | uspto-grants-2015_05 |
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| ORD ID | ord-281c048aa3bc4786a9fa55ad353ca83f |
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| Source note | uspto-grants-2015_05 |
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