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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 573705Generated: October 31, 2026

4-Iodobenzonitrile → 4-((S)-((S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(hydroxy)methyl)benzonitrile

https://huagongshe.com/reaction/573705

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IodobenzonitrileHCID 76467—
Reactant(S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carbaldehydeHCID 86662512—
Product4-((S)-((S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(hydroxy)methyl)benzonitrileHCID 66761466—

Reaction Steps

Obtained by starting from (S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carbaldehyde and 4-iodobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029544B2
Source datasetuspto-grants-2015_05
ORD IDord-feb20da0f13d436a9ffa89e0c5408d71
Source noteuspto-grants-2015_05