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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 573708Generated: October 31, 2026

1-Iodo-4-isobutylbenzene → (S)-((S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(4-isobutylphenyl)methanol

https://huagongshe.com/reaction/573708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Iodo-4-isobutylbenzeneHCID 11391295—
Reactant(S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carbaldehydeHCID 86662512—
Product(S)-((S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(4-isobutylphenyl)methanolHCID 66762498—

Reaction Steps

Obtained by starting from (S)-5-(tert-butyldimethylsilyloxy)-4-iodo-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carbaldehyde and 1-iodo-4-isobutylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029544B2
Source datasetuspto-grants-2015_05
ORD IDord-f744864a69d645f38513a1171ca900e0
Source noteuspto-grants-2015_05