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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 573750Generated: October 30, 2026

HCID 86662525, compound → ((S)-5-(tert-butyldimethylsilyloxy)-2-cyclopentyl-4-iodo-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(4-isopropylphenyl)methanol

https://huagongshe.com/reaction/573750

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86662525HCID 86662525—
ReactantHCID 178439193HCID 178439193—
Product((S)-5-(tert-butyldimethylsilyloxy)-2-cyclopentyl-4-iodo-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-3-yl)(4-isopropylphenyl)methanolHCID 66762260—

Reaction Steps

Obtained by starting from (S)-5-(tert-butyldimethylsilyloxy)-2-cyclopentyl-4-iodo-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carbaldehyde and 4-iso-propylphenylmagnesium bromide. The product is obtained as a diastereomic mixture, which is used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029544B2
Source datasetuspto-grants-2015_05
ORD IDord-d335bb347a454ff8aaf459aa2ef1343f
Source noteuspto-grants-2015_05