HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl methyl(4-nitrophenyl)propanedioate → HCID 12370795, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl methyl(4-nitrophenyl)propanedioate | HCID 12380744 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 12370795 | HCID 12370795 | — |
Reaction Steps
To a solution of 4.98 g Diethyl 2-methyl-2-(4-nitrophenyl)malonate in 70 ml methanol are added 896 mg of 10% palladium on charcoal. The mixture is hydrogenated at 2 bar for 3 hours. After filtration the solvent is evaporated in vacuo and the residue is chromatographed on silica gel (cyclohexane/ethylacetate 90:10 to 50:50).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029544B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-cbaa9f64a1554666b60f7b93d1ca5659 |
| Source note | uspto-grants-2015_05 |