HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-(isocyanatomethyl)phenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole → 1-[(5-chloro-2-isopropyl-phenyl)carbamothioyl]-3-[[3-[1-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazol-3-yl]phenyl]methyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-(isocyanatomethyl)phenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole | HCID 90412150 | — |
| Reactant | 1-(5-Chloro-2-isopropylphenyl)thiourea | HCID 90412442 | — |
| Product | 1-[(5-chloro-2-isopropyl-phenyl)carbamothioyl]-3-[[3-[1-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazol-3-yl]phenyl]methyl]urea | HCID 90413091 | — |
Reaction Steps
The title compound was prepared as described in Example 75 using 3-(3-(isocyanatomethyl)phenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole (CB34) and 1-(5-chloro-2-isopropylphenyl)thiourea (CB32) and isolated as an off-white solid (0.170 g, 38%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029560B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-2c5ab00a26e943bea931c920c1a42483 |
| Source note | uspto-grants-2015_05 |