Aluminium lithium hydride → HCID 86674041, compound

Participants

Reaction Steps

Under an argon atmosphere, 3,4,5-tris(octadecyloxy)benzyl azide (3.00 g, 3.21 mmol) was dissolved in dehydrating tetrahydrofuran (35 mL) and, under ice-cooling, lithium aluminum hydride (162 mg, 4.30 mmol) was added. The reaction mixture was stirred at room temperature for 2 hr. After completion of the reaction, purified water (2 mL) and 4.0 mol/L aqueous sodium hydroxide solution (2 mL) were added dropwise to the reaction mixture to decompose unreacted lithium aluminum hydride, and the reaction mixture was filtered through celite. The filtrate was concentrated under reduced pressure, acetonitrile was added, and the precipitated solid was collected by filtration and dried under reduced pressure to quantitatively give the title compound (3.09 g) as a white solid.

Provenance & Evidence