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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574102Generated: October 30, 2026

Dimethyl Sulfate → 1,2,3-Trifluoro-5-methoxy-4-nitrobenzene

https://huagongshe.com/reaction/574102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfateHCID 6497—
Reactant3,4,5-Trifluoro-2-nitrophenolHCID 53880990—
Product1,2,3-Trifluoro-5-methoxy-4-nitrobenzeneHCID 26596869—

Reaction Steps

Staring from 3,4,5-trifluoro-2-nitrophenol and dimethyl sulfate in place of allyl bromide and using a procedure analogous to that used to prepare Intermediate 6,3,4,5-trifluoro-2-nitro-phenyl methyl ether was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034861B2
Source datasetuspto-grants-2015_05
ORD IDord-5017ef80f8174dbab71a1cf7b26849c6
Source noteuspto-grants-2015_05