反应详情

温度

40 °C

To a solution of the product of 1d (13.0 mmol) in 100 mL methanol sodium hydroxide (20.0 mmol) was added. The mixture was stirred for 2.5 hours at 40° C. and then evaporated to dryness. The remaining solid was stirred with 100 mL water and the pH was adjusted to about 6 with concentrated acetic acid. The precipitated product was isolated by filtration, washed with water and dried at 60° C.

1. customevaporated to dryness
2. stirringThe remaining solid was stirred with 100 mL water
3. customThe precipitated product was isolated by filtration
4. washwashed with water
5. customdried at 60° C.