2-(Tributylstannyl)pyridine → HCID 6417974, compound

Participants

Reaction Steps

Stille coupling starting from the 6,6′-dichloro-3,3′-bipyridazine 17 was subsequently carried out in the presence of two mol of tributylstannylpyridine 18 and 10% of Pd(PPh3)4 catalyst, so as to give a new 6,6′-bis(pyridin-2-yl)-3,3′-bipyridazine 19 with a yield of 62% (Scheme 8). In parallel, the formation of the homocoupling product 21 (23%) was observed. The use of an excess of organostannane makes the purification of the dimer more difficult.

Provenance & Evidence