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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574400Generated: October 31, 2026

Hydrochloric Acid → HCID 59161623, compound

https://huagongshe.com/reaction/574400

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 23932524HCID 23932524—
SolventEthanolHCID 702—
ProductHCID 59161623HCID 59161623—

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of ethyl 3-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)propanoate (See Example 54A) (1.5 g) and NaOH (3N, 30 ml) in ethanol (30 ml) was stirred at 50° C. for 3 h after which it was cooled to room temperature and neutralized with concentrated HCl. The solvent was removed under reduced pressure to obtain crude 3-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)propanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034880B2
Source datasetuspto-grants-2015_05
ORD IDord-4d9e2a68c46a4b7ab27e50fa6a700b7a
Source noteuspto-grants-2015_05