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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574462Generated: October 31, 2026

2-Methyl-5-vinylpyridine → HCID 57876167, compound

https://huagongshe.com/reaction/574462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-vinylpyridineHCID 8817—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 68922038HCID 68922038—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 57876167HCID 57876167—

Reaction Steps

The title compound is prepared from a mixture of 1,2-dihydro-1-hydroxy-2,8-dimethyl-4H-pyrido[4,3-b]indol-3(5H)-one, 2-methyl-5-vinylpyridine and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034880B2
Source datasetuspto-grants-2015_05
ORD IDord-13ff81871e904e17852e6eb20fb4e578
Source noteuspto-grants-2015_05