HRID574653

反应详情

EQUATION

反应方程式

HRID 574653 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model# SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).

WORKUP

后处理

  1. customThe wet pellets are dried (Fluid Air Model#0050)
  2. filtrationsieved (30 mesh<Acceptable<20 mesh)