2-(3-(4-methyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dione → 3-(4-Methyl-1H-imidazol-1-yl)propan-1-amine

HRID 574693Notes

Reaction equation

HRID 574693 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][N:5]([CH2:7][CH2:8][CH2:9][N:10]2C(=O)C3C(=CC=CC=3)C2=O)[CH:6]=1.CC1N(CCCN2C(=O)C3C(=CC=CC=3)C2=O)C=NC=1>>[CH3:1][C:2]1[N:3]=[CH:4][N:5]([CH2:7][CH2:8][CH2:9][NH2:10])[CH:6]=1

Participants

3

Reactant 2

HCID 136181202-(3-(4-methyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dioneHCID 187222662-(3-(5-methyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dione

Product 1

HCID 150349543-(4-Methyl-1H-imidazol-1-yl)propan-1-amine

Procedure

Yield: 6.1 g (62.0%) of a mixture of 2-(3-(4-methyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dione and 2-(3-(5-methyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dione

Sources & evidence

ORD record
ord-ad16ef01a9cd4aa6ad466ae70120d0ee
Source dataset
uspto-grants-2015_05
Patent number
US09034907B2

Reaction notes

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