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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574702Generated: October 27, 2026

Methyl 2-isothiocyanato-4,5-dimethylthiophene-3-carboxylate → 2,3-dihydro-5,6-dimethyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-2-thioxothieno[2,3-d]pyrimidin-4(1H)-one

https://huagongshe.com/reaction/574702

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-isothiocyanato-4,5-dimethylthiophene-3-carboxylateHCID 3459267—
Reactant3-(5-methyl-1H-imidazol-1-yl)propan-1-amineHCID 19429483—
Product2,3-dihydro-5,6-dimethyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-2-thioxothieno[2,3-d]pyrimidin-4(1H)-oneHCID 25100042—

Reaction Steps

The compound was synthesized starting from methyl 2-isothiocyanato-4,5-dimethylthiophene-3-carboxylate (0.1 g, 0.44 mmol) and 3-(5-methyl-1H-imidazol-1-yl)propan-1-amine (5) (0.06 g, 0.44 mmol) as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034907B2
Source datasetuspto-grants-2015_05
ORD IDord-2c80f7661d4a4ddca993bdbacac2e0a9
Source noteuspto-grants-2015_05