1H-Imidazole-1-propanamine → HCID 25100520, compound
Reaction equation
[N:1]([C:4]1[C:8]([CH3:9])=[CH:7][S:6][C:5]=1[C:10]([O:12]C)=O)=[C:2]=[S:3].[N:14]1([CH2:19][CH2:20][CH2:21][NH2:22])[CH:18]=[CH:17][N:16]=[CH:15]1>>[CH3:9][C:8]1[C:4]2[NH:1][C:2](=[S:3])[N:22]([CH2:21][CH2:20][CH2:19][N:14]3[CH:18]=[CH:17][N:16]=[CH:15]3)[C:10](=[O:12])[C:5]=2[S:6][CH:7]=1Participants
3
Procedure
The compound was synthesized starting from methyl 3-isothiocyanato4-methylthiophene-2-carboxylate (0.853 g, 4.0 mmol) and 3-(1H-imidazol-1-yl)propan-1-amine (0.5 g, 4.0 mmol) as described above.
Workup
- customThe compound was synthesized
Sources & evidence
- ORD record
- ord-00653a67f20e4f84b309419d49f60261
- Source dataset
- uspto-grants-2015_05
- Patent number
- US09034907B2
Reaction notes
Loading…