1H-Imidazole-1-propanamine → HCID 25100665, compound
Reaction equation
[N:1]([C:4]1[S:8][C:7]2[CH2:9][CH2:10][CH2:11][C:6]=2[C:5]=1[C:12]([O:14]C)=O)=[C:2]=[S:3].[N:16]1([CH2:21][CH2:22][CH2:23][NH2:24])[CH:20]=[CH:19][N:18]=[CH:17]1>>[N:16]1([CH2:21][CH2:22][CH2:23][N:24]2[C:12](=[O:14])[C:5]3[C:6]4[CH2:11][CH2:10][CH2:9][C:7]=4[S:8][C:4]=3[NH:1][C:2]2=[S:3])[CH:20]=[CH:19][N:18]=[CH:17]1Participants
3
Procedure
The compound was synthesized starting from methyl 5,6-dihydro-2-isothiocyanato-4H-cyclopenta[b]thiophene-3-carboxylate (0.018 g.0.08 mmol) and 3-(1H-imidazol-1-yl)propan-1-amine (0.009 g, 0.08 mmol) as described above.
Workup
- customThe compound was synthesized
Sources & evidence
- ORD record
- ord-359c8c50c0ac43b7804bcbff7994efa0
- Source dataset
- uspto-grants-2015_05
- Patent number
- US09034907B2
Reaction notes
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