HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-nitrobenzenesulfonamide → 3-cyano-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
| Reactant | 4-Methylpiperazin-1-ylamine dihydrochloride hydrate | HCID 198221 | — |
| Reactant | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| Product | 3-cyano-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide | HCID 67126501 | — |
Reaction Steps
The title compound was prepared by substituting EXAMPLE 52A for 4-chloro-3-nitrobenzenesulfonamide and (tetrahydro-2H-pyran-4-yl)methanamine for 4-methylpiperazin-1-amine dihydrochloride in EXAMPLE 6A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034875B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-048d1d1346434106a465c864006aba1f |
| Source note | uspto-grants-2015_05 |