1,14-Diamino-3,6,9,12-tetraoxatetradecane → HCID 178497274, compound

HRID 574999Notes

Reaction equation

HRID 574999 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([C:23](O)=[O:24])[C:11]3[C:16]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[N:15][NH:14][C:12]=3[N:13]=2)=[CH:4][C:3]=1[C:26]([O:28][CH3:29])=[O:27].[CH2:30]([NH2:45])[CH2:31][O:32][CH2:33][CH2:34][O:35][CH2:36][CH2:37][O:38][CH2:39][CH2:40][O:41][CH2:42][CH2:43][NH2:44]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[C:12]3[NH:14][N:15]=[C:16]([C:17]4[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=4)[C:11]3=[C:10]([C:23](=[O:24])[NH:44][CH2:43][CH2:42][O:41][CH2:40][CH2:39][O:38][CH2:37][CH2:36][O:35][CH2:34][CH2:33][O:32][CH2:31][CH2:30][NH:45][C:23]([C:10]3[CH:9]=[C:8]([C:5]4[CH:6]=[CH:7][C:2]([F:1])=[C:3]([C:26]([O:28][CH3:29])=[O:27])[CH:4]=4)[N:13]=[C:12]4[NH:14][N:15]=[C:16]([C:17]5[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=5)[C:11]=34)=[O:24])[CH:9]=2)=[CH:4][C:3]=1[C:26]([O:28][CH3:29])=[O:27]

Participants

3

Reactant 2

HCID 101985981,14-Diamino-3,6,9,12-tetraoxatetradecaneHCID 178497275HCID 178497275, compound

Product 1

HCID 178497274HCID 178497274, compoundYield 66%

Procedure

Obtained according to the process described in Step 1.10, using 6-[4-fluoro-3-(methoxycarbonyl)phenyl]-3-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid [described in Step 1.9.] and 3,6,9,12-tetraoxatetradecane-1,14-diamine, in the form of a white powder (yield: 66%).

Workup

  1. customObtained

Sources & evidence

ORD record
ord-eeae8d33d931407cac5e1ffb941310f7
Source dataset
uspto-grants-2015_05
Patent number
US09034898B2

Reaction notes

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