HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 4-((N,N-Dimethylamino)methyl)phenylboronic acid pinacol ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-(4-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 3734506 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-((N,N-Dimethylamino)methyl)phenylboronic acid pinacol ester | HCID 3460459 | — |
Reaction Steps
A mixture of 2-(4-(bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (200 mg, 0.673 mmol) and aqueous Me2NH (4 mL) in THF (10 mL) was stirred at room temperature overnight. It was then concentrated under reduced pressure to give the title compound. MS (m/z): 262 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434726B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-acbd8a8c17224c1387a500bd99a71009 |
| Source note | uspto-grants-2016_09 |