HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-Bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide → Methyl 4-(2-carbamoyl-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-10-yl)-2-hydroxy-2-methylbut-3-ynoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-Bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide | HCID 86693051 | — |
| Reactant | Methyl 2-hydroxy-2-methylbut-3-ynoate | HCID 86693195 | — |
| Product | Methyl 4-(2-carbamoyl-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-10-yl)-2-hydroxy-2-methylbut-3-ynoate | HCID 86693109 | — |
Reaction Steps
Similar to as described in General Procedure G, 10-bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide was reacted with methyl 2-hydroxy-2-methylbut-3-ynoate to give the titled compound as a brown oil. M+1=374
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034866B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-272a99dc5bbd4ebcb2060be6af48372f |
| Source note | uspto-grants-2015_05 |