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HRID575190

反应详情

EQUATION

反应方程式

HRID 575190 的结构方程式

REACTANTS

反应物

2
结构：NC(=O)c1nc2c(s1)CCOc1ccc(Br)cc1-2
HCID58203902

未命名化合物

结构：C#CC1(O)CCN(C)C1=O
HCID58221634

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2CCO3)C1=O
HCID71666344

未命名化合物

收率 48%

PROCEDURE

实验过程

Similar to as described in General Procedure G, 9-bromo-4,5-dihydrobenzo[2,3]oxepino[4,5-d]thiazole-2-carboxamide) was reacted with 3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one (WO2009/158011 A1) to give the titled compound as a brown solid (56.1 mg, 48%).